Dealing with Anxiety Through the Use of Naltrexone

Whether it’s a symptom of a disorder or the disorder itself, dealing with anxiety can be hard.

You feel your heart beat racing. Your pulse has increased. You’re sweating. You’re not getting much sleep.

Your pulse has increased. You’re sweating. You’re not getting much sleep.

You’re sweating. You’re not getting much sleep.

You’re not getting much sleep.

And you just can’t stop your mind from racing.

Perhaps it’s time to discuss with your physician about Naltrexone.

Naltrexone is an opiate receptor antagonist. Meaning it prevents opiates from binding to your body’s receptors.

What does this entail?

It will curb recreational drug and alcohol use. Since the medical drug blocks ingested opiates.

How does it help with anxiety?

Naltrexone also blocks endogenous opiates, which are endorphins, from binding as well.

You’re probably thinking that by blocking these receptors and restricting the endorphins, your anxiety will increase.

Not quite.

Read on to find out how Naltrexone helps those dealing with anxiety.

Brief history of Naltrexone

During the 1980s, opioid antagonists gained notoriety for blocking receptors in the body. During this time, American Neuroscientist, John David Sinclair made a discovery.

To curb alcoholism, he had to prevent the endorphins from binding to the receptors.

As an Atlantic article states, he realized this would curb alcoholism.

In case you don’t know, endorphins are chemicals responsible for making you feel happy.

We normally associate them with exercise. But there are other ways for them to be released.

In fact, they’re heavily involved in addiction. Because they chemically reward the addict for taking the addictive substance.

Sinclair’s studies proved just that.

As, with no chemical reward, people started to become less and less dependent on alcohol.

In 1994, the FDA approved Naltrexone to treat alcohol abuse.

It is now used to treat drug addiction and other disorders. These include:

  • Major depression
  • Obsessive-compulsive disorder, more commonly known as OCD (which is in the anxiety family)
  • Drug and alcohol addiction (withdrawal symptoms including cravings)
  • Eating disorders
  • Bipolar disorder
  • And yes, anxiety disorders

How does it help dealing with anxiety?

We mentioned that Naltrexone prevents endorphins from binding with receptors.

Using a full dosage, it will treat alcohol and drug addiction.

But in small doses, it will trick your brain believe it has fewer endorphin circuits. To compensate for this, your brain will activate these pathways, increasing your endorphins.

Releasing more endorphins helps those dealing with anxiety. Because endorphins are natural painkillers.


A study involving 22 fibromyalgia patients showed positive results when taking Naltrexone.

Assistant Professor of Medicin at the University of California, Los Angeles, Dr. Metyas, MD, conducted the study.

In an MPR article, he stated, ” The patients reported decreases in anxiety, pain, and sleeping habits from baseline.”

Other people have seen positive results as well. For example, This woman who has Sjogren’s syndrome (an immune system disorder).

Word of caution

Please note that medical drug reaction depends on the individual’s body. While some have received positive results from Naltrexone, some have not.

So, consult a credited physician about Naltrexone before taking it.

Also, note you cannot take narcotic pain medication while on them. As Naltrexone blocks ingested opiates from reaching the receptor.

Want more information about dealing with anxiety and Naltrexone? Check out our blog!

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