Want to find out how LDN works?
Naltrexone has been FDA-approved for treating opioid and alcohol addiction. Plus, low dose naltrexone has also been used for people with chronic illnesses.
Keep reading because this article will explain how LDN works and how it could help you.
The Effects of Drug and Alcohol Abuse
Opiates like opium produce a feeling of pleasure and reduction in pain. It is addictive because the rush lasts for a short time and then your body returns to its normal state.
To feel good, you need more opiates in your system. Alcohol works in a similar way, producing feel-good chemicals in your body that later go away.
Addiction happens because you need the drug or alcohol to feel good again.
Addiction can cause major health problems, relationship problems, job loss, and loss of a sense of purpose. It can have devastating, long-term effects on your life and wellbeing.
It can be extremely difficult to stop using drugs and alcohol on your own because of withdrawal symptoms. Most people need professional help from counselors and rehab specialists to regain control of their life after developing an opioid addiction.
How LDN Works
Our body naturally produces endorphins (endogenous morphine).
Endorphins are molecules that also ease pain and have a similar effect on the body as opiates and alcohol but without the withdrawal symptoms.
One type of endorphin is called opioid growth factor (OGF), also known as Met-Enkephalin. These endorphins help regulate cell growth, and they help the immune system work correctly.
In order for opioid growth factors to take effect, they have to bind to opioid growth factor receptors (OGFR) that are located on the surface of your body’s cells.
Then your body would experience a reduction in pain and feeling of pleasure.
What Naltrexone does is that it blocks OGF from binding to OGFR, and prevents the rush of pleasure your body experiences. This means that when a person uses opiates or alcohol, it doesn’t make them feel good.
Low dose naltrexone prevents OGF from binding to its receptor because they’re all filled with naltrexone.
Your body creates more opioid growth factor receptors that are more sensitive to OGF to compensate for the lack of effectively-bound OGF.
OGF builds up in your body, as well.
Taking a low dose of naltrexone that is quickly metabolized, or broken down by the body, can have a beneficial effect that works for more than just substance addiction.
You take a low dose, so the body creates more OGFR, makes OGFR more sensitive to OGF, and produces more OGF.
Then once your body gets rid of the naltrexone, all that extra OGF can bind to the extra OGF receptors with a heightened sensitivity to OGF.
LDN for Treating Other Health Problems
Not having enough endorphins can produce immune system disorders too.
While taking naltrexone, your body can increase the power of the immune system as you enhance the binding power of endorphins to their receptors.
LDN can help treat other health problems with this mechanism, including:
- Inflammatory Bowel Disease (IBD)
- Alzheimer’s Disease
- Parkinson’s Disease
- Post-Traumatic Stress Disorder (PTSD)